AZ12672857
AZ12672857 is a potent and selective EphB4 inhibitor with an IC50 of 1.3 nM. It effectively blocks EphB4 autophosphorylation and cellular proliferation in relevant assays, making it a valuable chemical probe for studying EphB4 signaling in cancer research and angiogenesis, both in vitro and in vivo.
Product Specifications
CAS Number
945396-55-4
Product Name Alternative
C-Src, AZ 12672857, AZ12672857, AZ-12672857, EphB4, EphrinReceptor, Ephrin Receptor
Field of Research
Cardiovascular Research, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.05% (May vary between batches)
Solubility
DMSO:50 mg/mL (102.76 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.11 mM)
Smiles
CN (c1ccnc (Nc2cc (cc (c2) N2CCOCC2) N2CCOCC2) n1) c1cccc2[nH]ncc12
Molecular Formula
C26H30N8O2
Molecular Weight
486.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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