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GSK778 hydrochloride

GSK778 hydrochloride is a potent and selective BD1 bromodomain inhibitor of BET proteins, demonstrating low nanomolar IC50 values. It mimics pan-BET inhibitor effects in cancer models, making it a valuable tool for epigenetic research in oncology, applicable in both cellular and in vivo studies of transcriptional regulation and tumor progression.

Product Specifications

CAS Number

2863657-79-6

Product Name Alternative

BET, EpigeneticReaderDomain, Epigenetic Reader Domain, GSK-778 Hydrochloride, GSK778 Hydrochloride, GSK778 hydrochloride, GSK 778 Hydrochloride

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

97.26% (May vary between batches)

Solubility

DMSO:50 mg/mL (91.23 mM)

Smiles

C[C@@H] (N1C (COC) =NC2=C1C3=CC (OC[C@@H]4CNCC4) =C (C5=C (C) ON=C5C) C=C3N=C2) C6=CC=CC=C6.[H]Cl

Molecular Formula

C30H34ClN5O3

Molecular Weight

548.08

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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