Aplidine
Aplidine is a potent antiviral agent against SARS-CoV-2 (IC90 = 0.88 nM) and an anti-cancer compound targeting EEF1A2 (Kd = 80 nM) . Its applications span oncology and virology research, with studies demonstrating activity in both in vitro cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
137219-37-5
Product Name Alternative
DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, COVID-19, advanced cancer, Advanced Malignancies, Aplidine, Antiviral, anticancer, infection, inhibit, Inhibitor, MOLT-4, Plitidepsin, Leukemia, EEF1A2, SARS-CoV, SARS-CoV-2, SARS coronavirus, SARSCoV, RNA Synthesis, RNASynthesis, VEGF
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (2.97 mM) ; DMSO:50 mg/mL (45.03 mM)
Smiles
[H][C@@]12CCCN1C (=O) [C@H] (CC (C) C) NC (=O) [C@@H] (C) C (=O) [C@@H] (OC (=O) C[C@H] (O) [C@] ([H]) (NC (=O) [C@@H] (NC (=O) [C@@H] (CC (C) C) N (C) C (=O) [C@@H]1CCCN1C (=O) C (C) =O) [C@@H] (C) OC (=O) [C@H] (Cc1ccc (OC) cc1) N (C) C2=O) [C@@H] (C) CC) C (C) C
Molecular Formula
C57H87N7O15
Molecular Weight
1110.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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