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Zanubrutinib

Zanubrutinib (BGB-3111) is a potent and selective small molecule Bruton's tyrosine kinase (BTK) inhibitor. It is widely used in biochemical and cellular research to investigate B-cell receptor signaling and has demonstrated efficacy in preclinical in vivo models of B-cell malignancies.

Product Specifications

CAS Number

1691249-45-2

Product Name Alternative

Inhibitor, inhibit, Bruton tyrosine kinase, BGB 3111, BGB3111, BGB-3111, Btk, BTK, zanubrutinib

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.42% (May vary between batches)

Solubility

DMSO:257.5 mg/mL (546.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.6 mM)

Smiles

NC (=O) c1c2NCC[C@@H] (C3CCN (CC3) C (=O) C=C) n2nc1-c1ccc (Oc2ccccc2) cc1

Molecular Formula

C27H29N5O3

Molecular Weight

471.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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