AZD-5069
AZD-5069 is a potent and selective small molecule antagonist of the CXCR2 chemokine receptor, exhibiting an IC50 of 0.79 nM. It has been utilized in preclinical research to investigate the role of CXCR2 in inflammatory diseases, including studies in models of COPD, asthma, and cancer.
Product Specifications
CAS Number
878385-84-3
Product Name Alternative
CXCR2, CXC chemokine receptors, CXCR, AZD5069, AZD-5069, AZD 5069, Inhibitor, inhibit
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.38% (May vary between batches)
Solubility
DMSO:90 mg/mL (188.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.93 mM)
Smiles
C[C@@H] (Oc1cc (NS (=O) (=O) N2CCC2) nc (SCc2cccc (F) c2F) n1) [C@@H] (O) CO
Molecular Formula
C18H22F2N4O5S2
Molecular Weight
476.52
Storage Conditions
-20°C
Notes
For research use only.
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