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AZD-5069

AZD-5069 is a potent and selective small molecule antagonist of the CXCR2 chemokine receptor, exhibiting an IC50 of 0.79 nM. It has been utilized in preclinical research to investigate the role of CXCR2 in inflammatory diseases, including studies in models of COPD, asthma, and cancer.

Product Specifications

CAS Number

878385-84-3

Product Name Alternative

CXCR2, CXC chemokine receptors, CXCR, AZD5069, AZD-5069, AZD 5069, Inhibitor, inhibit

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

98.38% (May vary between batches)

Solubility

DMSO:90 mg/mL (188.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.93 mM)

Smiles

C[C@@H] (Oc1cc (NS (=O) (=O) N2CCC2) nc (SCc2cccc (F) c2F) n1) [C@@H] (O) CO

Molecular Formula

C18H22F2N4O5S2

Molecular Weight

476.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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