A-317491
A-317491 (ABT 202) is a potent, non-nucleotide antagonist of P2X3 (Ki: 22 nM) and P2X2/3 (Ki: 9 nM) receptors, effectively inhibiting receptor-mediated calcium flux. This compound is widely used in vitro and in vivo to investigate purinergic signaling in pain, cough, and inflammatory pathways.
Product Specifications
CAS Number
475205-49-3
Product Name Alternative
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
96.10% (May vary between batches)
Solubility
Ethanol:90 mg/mL (159.13 mM) ; DMSO:47 mg/mL (83.1 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.54 mM)
Smiles
OC (=O) c1cc (C (O) =O) c (cc1C (O) =O) C (=O) N (Cc1cccc (Oc2ccccc2) c1) [C@H]1CCCc2ccccc12
Molecular Formula
C33H27NO8
Molecular Weight
565.57
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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