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2-Hydroxy atorvastatin calcium salt

2-Hydroxy atorvastatin calcium salt is a major metabolite of the HMG-CoA reductase inhibitor atorvastatin, exhibiting potent inhibitory activity with an IC50 of 8 nM. This compound is widely used in pharmacological research to study statin metabolism, pharmacokinetics, and efficacy in both in vitro enzyme assays and in vivo animal models of hyperlipidemia.

Product Specifications

CAS Number

265989-46-6

Product Name Alternative

2 Hydroxy atorvastatin calcium salt, 2-Hydroxy atorvastatin, 2-Hydroxy atorvastatin calcium, 2Hydroxy atorvastatin calcium salt, Drug Metabolite, DrugMetabolite, inhibit, Inhibitor

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

97.06% (May vary between batches)

Solubility

DMSO:10 mg/mL (16.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.68 mM)

Smiles

[Ca++].CC (C) c1c (C (=O) Nc2ccccc2O) c (c (-c2ccc (F) cc2) n1CC[C@@H] (O) C[C@@H] (O) CC ([O-]) =O) -c1ccccc1.CC (C) c1c (C (=O) Nc2ccccc2O) c (c (-c2ccc (F) cc2) n1CC[C@@H] (O) C[C@@H] (O) CC ([O-]) =O) -c1ccccc1

Molecular Formula

C66H68CaF2N4O12

Molecular Weight

1187.36

Storage Conditions

Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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