Navoximod
Navoximod (GDC-0919) is a potent small molecule inhibitor of the indoleamine 2,3-dioxygenase (IDO) pathway, exhibiting a Ki of 7 nM and an EC50 of 75 nM. It has been utilized in both in vitro and in vivo research to investigate immunomodulation, particularly in the fields of oncology and autoimmune disease.
Product Specifications
CAS Number
1402837-78-8
Product Name Alternative
Indoleamine 2,3-Dioxygenase, Indoleamine 2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase (IDO), Indoleamine2,3Dioxygenase, inhibit, Indoleamine2,3Dioxygenase (IDO), Navoximod, NLG 919, NLG-919, NLG-?919, NLG919, NLG-919, Inhibitor, GDC 0919, GDC0919, GDC-0919, IDO
Field of Research
Metabolism Research
Purity
99.37% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.64 mM) ; DMSO:100 mg/mL (316.09 mM)
Smiles
[H][C@@]1 (CC[C@H] (O) CC1) [C@H] (O) C[C@H]1c2c (cccc2F) -c2cncn12
Molecular Formula
C18H21FN2O2
Molecular Weight
316.37
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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