INCB3344
INCB3344 is a potent, selective, and orally bioavailable CCR2 antagonist, demonstrating low nanomolar IC50 values in both binding and chemotaxis assays for mouse and human CCR2. It is a valuable research tool for investigating CCR2-mediated pathways in inflammatory and metabolic diseases in both in vitro and in vivo models.
Product Specifications
CAS Number
1262238-11-8
Product Name Alternative
CCR2, CC chemokine receptor, CCR, INCB 3344, INCB3344, INCB-3344, inhibit, Inhibitor
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:145 mg/mL (251.04 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (8.66 mM) ; H2O:Insoluble
Smiles
[H][C@@]1 (CC[C@] (O) (CC1) c1ccc2OCOc2c1) N1C[C@H] (NC (=O) CNC (=O) c2cccc (c2) C (F) (F) F) [C@H] (C1) OCC
Molecular Formula
C29H34F3N3O6
Molecular Weight
577.59
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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