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EIPA

EIPA (L593754) is a dual inhibitor of TRPP3 channels (IC50=10.5 μM) and Na+/H+ exchangers (NHE) . It is a research tool used to study autophagy, cell volume regulation, and processes relevant to cancer and inflammatory disease models in both cellular and animal studies.

Product Specifications

CAS Number

1154-25-2

Product Name Alternative

Sodium Channel, Sodium-hydrogen Exchanger, Sodium/hydrogen Exchanger, SodiumChannel, zinc, Prostaglandin Receptor, renal failure, Transient receptor potential channels, TRP Channel, TRPVChannel, TRPV Channel, TRPP3 channel, TRPChannel, MH 12-43, pancreatic carcinoma, NHE3, Na+/H+ Exchanger (NHE), Na+/H+-exchanger (NHE), MKN28, neuron, kainite, inhibit, L 593754, Inhibitor, gastric cancer, IEC-18, IECs, IBDs, L593754, L-593754, EIPA, ddY strain mice, Cyclooxygenase, COX, colon carcinoma, Autophagy, calcium, Cation channel

Field of Research

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

95.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.34 mM) ; DMSO:135 mg/mL (450.36 mM)

Smiles

CCN (C (C) C) c1nc (N) c (nc1Cl) C (=O) NC (N) =N

Molecular Formula

C11H18ClN7O

Molecular Weight

299.76

Storage Conditions

Keep away from moisture, keep away from direct sunlight, store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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