Mavorixafor
Mavorixafor (AMD-070) is a potent and selective CXCR4 antagonist with a 13 nM IC50 for receptor binding. It effectively blocks T-tropic HIV-1 replication in vitro, showing IC50 values of 1 nM and 9 nM in MT-4 cells and PBMCs, respectively. Its research applications extend to oncology and immunology, including studies on cancer metastasis and stem cell mobilization.
Product Specifications
CAS Number
558447-26-0
Product Name Alternative
CXCR4, CXCR, CXC chemokine receptors, AMD 070, AMD070, AMD-070, inhibit, Inhibitor, HIV, Mavorixafor, Human immunodeficiency virus
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.56% (May vary between batches)
Solubility
Smiles
N (CC=1NC=2C (N1) =CC=CC2) (CCCCN) [C@@H]3C=4C (CCC3) =CC=CN4
Molecular Formula
C21H27N5
Molecular Weight
349.47
Storage Conditions
Store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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