NEO2734
NEO2734 is a potent dual inhibitor of the p300/CBP and BET bromodomain families, exhibiting IC50 values below 30 nM for both targets. This orally bioavailable small molecule is a valuable chemical probe for epigenetic research in oncology, enabling mechanistic studies in both cellular and animal models of cancer.
Product Specifications
CAS Number
2081072-29-7
Product Name Alternative
NEO2734, NEO-2734, NEO 2734, inhibit, MYC, Inhibitor, HAT, HATs, Histone Acetyltransferase, HistoneAcetyltransferase, Epigenetic Reader Domain, EpigeneticReaderDomain, EP 31670, EP31670, EP-31670, CBP, BET bromodomain, SPOP, TC-797, p300, p300/CBP, PER-403
Field of Research
Epigenetics & Chromatin
Purity
98.56% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (63.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.59 mM)
Smiles
Cc1cc (cn (C) c1=O) -c1ccc2nc (C3CCOCC3) n (CCOC (F) (F) F) c2c1
Molecular Formula
C22H24F3N3O3
Molecular Weight
435.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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