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Rubrofusarin gentiobioside

Rubrofusarin gentiobioside is a research compound shown to downregulate TGF-β1 and fibronectin expression while inhibiting NF-κB DNA binding activity. These in vitro findings indicate its potential utility in studying the molecular pathways underlying AGE-related diabetic nephropathy and vascular complications.

Product Specifications

CAS Number

24577-90-0

Product Name Alternative

ERK, Inhibitor, inhibit, NF-κB, NFκB, NFkB, NF-kB, Rubrofusarin gentiobioside, Rubrofusarin-6-O-b-D-gentiobioside, Rubrofusarin-6-O-beta-D-gentiobioside, Rubrofusarin-6-O-β-D-gentiobioside, TGF-beta, TGFbeta/Smad, TGF-b/Smad, TGFb, TGFbeta, Smad, radical?scavenging, TGFβ, TGF-β/Smad

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

99.75% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (37.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.35 mM)

Smiles

COc1cc (O[C@@H]2O[C@H] (CO[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) [C@@H] (O) [C@H] (O) [C@H]2O) c2c (O) c3c (cc2c1) oc (C) cc3=O

Molecular Formula

C27H32O15

Molecular Weight

596.53

Storage Conditions

Keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

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