PF-00835231
PF-00835231 is a potent and selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating sub-nanomolar in vitro activity. As the active moiety of the first 3CLpro-targeting clinical candidate, it serves as a crucial research tool for studying coronavirus replication and for the development of antiviral therapeutics in both biochemical and cellular assays.
Product Specifications
CAS Number
870153-29-0
Product Name Alternative
SARS coronavirus, SARSCoV, SARS CoV-1, SARS CoV-1 3CLpro, SARS CoV-2, SARS-CoV, SARS-CoV-2, PF00835231, PF-00835231, PF 00835231, 3CLpro, COVID-19, Inhibitor, inhibit
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
97.83% (May vary between batches)
Solubility
DMSO:250 mg/mL (529.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.58 mM)
Smiles
COc1cccc2[nH]c (cc12) C (=O) N[C@@H] (CC (C) C) C (=O) N[C@@H] (C[C@@H]1CCNC1=O) C (=O) CO
Molecular Formula
C24H32N4O6
Molecular Weight
472.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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