GNE-9815
GNE-9815 is a highly selective RAF kinase inhibitor. It is used in preclinical research to target KRAS-mutant cancers, showing activity in both in vitro cellular assays and in vivo tumor models as part of combination therapeutic strategies.
Product Specifications
CAS Number
2729996-45-4
Product Name Alternative
Raf, KRAS, GNE9815, GNE-9815, GNE 9815, 3- (2-cyanopropan-2-yl) -N-[2-fluoro-4-methyl-5- (7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl) phenyl]benzamide
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.19% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.2 mM) ; DMSO:39.17 mg/mL (86 mM)
Smiles
Cc1cc (F) c (NC (=O) c2cccc (c2) C (C) (C) C#N) cc1-c1cnc2c (cnn (C) c2=O) c1
Molecular Formula
C26H22FN5O2
Molecular Weight
455.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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