AP26113
AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
Product Specifications
CAS Number
1197958-12-5
Purity
>98% (HPLC)
Solubility
Ethanol: 106 mg/mL (200.37 mM) ; DMSO: 45 mg/mL (85.06 mM)
Smiles
COC1=C (NC2=NC=C (Cl) C (NC3=CC=CC=C3P (C) (C) =O) =N2) C=CC (=C1) N1CCC (CC1) N (C) C
Molecular Formula
C26H34ClN6O2P
Molecular Weight
529.01
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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