Rigosertib sodium (b)
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Phase 3.
Product Specifications
CAS Number
1225497-78-8
Product Name Alternative
ON-01910
Purity
>98% (HPLC)
Solubility
Water: 95 mg/mL (200.64 mM) ; DMSO: 95 mg/mL (200.64 mM)
Smiles
COC1=C (C=C (C=C1) CS (=O) (=O) /C=C/C2=C (C=C (C=C2OC) OC) OC) NCC (=O) [O-].[Na+]
Molecular Formula
C21H24NNaO8S
Molecular Weight
473.47
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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