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TBA-354

TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.Bacterial Infection Phase 1 Clinical.

Product Specifications

CAS Number

1257426-19-9

Product Name Alternative

TBA354

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 46 mg/mL

Smiles

O=[N+] (C1=CN2C (OC[C@@H] (OCC3=CC=C (C4=CC=C (OC (F) (F) F) C=C4) N=C3) C2) =N1) [O-]

Molecular Formula

C19H15F3N4O5

Molecular Weight

436.3414

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4- (trifluoromethoxy) phenyl]-3-pyridinyl]methoxy]-, (6S) -

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