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ML-346

A novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.

Product Specifications

CAS Number

100872-83-1

Product Name Alternative

ML346

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 29 mg/mL

Smiles

O=C (NC (NC/1=O) =O) C1=C\C=C\C2=CC=C (OC) C=C2

Molecular Formula

C14H12N2O4

Molecular Weight

272.2561

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2,4,6 (1H,3H,5H) -Pyrimidinetrione, 5-[3- (4-methoxyphenyl) -2-propen-1-ylidene]-

Available Sizes

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