ML-346
A novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.
Product Specifications
CAS Number
100872-83-1
Product Name Alternative
ML346
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 29 mg/mL
Smiles
O=C (NC (NC/1=O) =O) C1=C\C=C\C2=CC=C (OC) C=C2
Molecular Formula
C14H12N2O4
Molecular Weight
272.2561
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,4,6 (1H,3H,5H) -Pyrimidinetrione, 5-[3- (4-methoxyphenyl) -2-propen-1-ylidene]-
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