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Tenovin-6

Tenovin-6 is an inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively.

Product Specifications

CAS Number

1011557-82-6

Purity

>98% (HPLC)

Solubility

Water: 98 mg/mL warmed (215.55 mM) ; DMSO: 98 mg/mL (215.55 mM)

Smiles

CN (C) CCCCC (=O) NC1=CC=C (NC (=S) NC (=O) C2=CC=C (C=C2) C (C) (C) C) C=C1

Molecular Formula

C25H34N4O2S

Molecular Weight

454.63

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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