Tenovin-6
Tenovin-6 is an inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively.
Product Specifications
CAS Number
1011557-82-6
Purity
>98% (HPLC)
Solubility
Water: 98 mg/mL warmed (215.55 mM) ; DMSO: 98 mg/mL (215.55 mM)
Smiles
CN (C) CCCCC (=O) NC1=CC=C (NC (=S) NC (=O) C2=CC=C (C=C2) C (C) (C) C) C=C1
Molecular Formula
C25H34N4O2S
Molecular Weight
454.63
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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