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LTX-315

LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical.

Product Specifications

CAS Number

1345407-05-7

Product Name Alternative

Oncopore

Purity

>98% (HPLC)

Solubility

Ethanol: 100 mg/mL (69.45 mM) ; DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

NCCCC[C@@H] (C (N) =O) NC ([C@H] (C (C1=CC=CC=C1) C2=CC=CC=C2) NC ([C@H] (CC3=CNC4=C3C=CC=C4) NC ([C@H] (CCCCN) NC ([C@H] (CCCCN) NC ([C@H] (CC5=CNC6=C5C=CC=C6) NC ([C@H] (CC7=CNC8=C7C=CC=C8) NC ([C@H] (CCCCN) NC ([C@H] (CCCCN) N) =O) =O) =O) =O) =O) =O) =O) =O

Molecular Formula

C78H106N18O9

Molecular Weight

1439.823

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

L-Lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-β-phenyl-L-phenylalanyl-L-lysinamide

Available Sizes

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