ML-241
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM) ; blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.
Product Specifications
CAS Number
1346528-06-0
Product Name Alternative
ML 241 | ML241
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1CCC2=C (C1) C (=NC (=N2) N3CCOC4=CC=CC=C43) NCC5=CC=CC=C5
Molecular Formula
C23H24N4O
Molecular Weight
372.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-benzyl-2- (2,3-dihydro-1,4-benzoxazin-4-yl) -5,6,7,8-tetrahydroquinazolin-4-amine
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