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ML-241

ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM) ; blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.

Product Specifications

CAS Number

1346528-06-0

Product Name Alternative

ML 241 | ML241

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

C1CCC2=C (C1) C (=NC (=N2) N3CCOC4=CC=CC=C43) NCC5=CC=CC=C5

Molecular Formula

C23H24N4O

Molecular Weight

372.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N-benzyl-2- (2,3-dihydro-1,4-benzoxazin-4-yl) -5,6,7,8-tetrahydroquinazolin-4-amine

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