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BIX02188 (c)

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.

Product Specifications

CAS Number

1094614-84-2

Purity

>98% (HPLC)

Solubility

DMSO: 100 mM

Smiles

CN (C) CC1=CC (=CC=C1) N/C (=C\2/C3=C (C=C (C=C3) C (=O) N) NC2=O) /C4=CC=CC=C4

Molecular Formula

C25H24N4O2

Molecular Weight

412.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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