BIX02188 (c)
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
Product Specifications
CAS Number
1094614-84-2
Purity
>98% (HPLC)
Solubility
DMSO: 100 mM
Smiles
CN (C) CC1=CC (=CC=C1) N/C (=C\2/C3=C (C=C (C=C3) C (=O) N) NC2=O) /C4=CC=CC=C4
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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