Plerixafor
Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7.Blood Cancer Approved.
Product Specifications
CAS Number
110078-46-1
Product Name Alternative
JM-3100 | AMD-3100 | SID-791
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1 (CN2CCNCCCNCCNCCC2) =CC=C (CN3CCNCCCNCCNCCC3) C=C1
Molecular Formula
C28H54N8
Molecular Weight
502.782
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis (methylene) ]bis-
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