I-BRD9
The first selective cellular chemical probe for BRD9 with pIC50 of 7.3; displays 700-fold selectivity over the BET family and 200-fold over the highly homologous BRD7; decreases cell proliferation, G1-arrest and apoptosis in rhabdoid tumor cells; shows synergistic inhibitory effects on cell proliferation combined with doxorubicin or carboplatin.
Product Specifications
CAS Number
1714146-59-4
Product Name Alternative
I-BRD9 | I-BRD-9 | I-BRD 9
Field of Research
Epigenetics & Chromatin
Purity
>98% (HPLC)
Solubility
DMSO: 15.5 mg/mL
Smiles
N=C (C (S1) =CC2=C1C (C3=CC=CC (C (F) (F) F) =C3) =CN (CC) C2=O) NC (CC4) CCS4 (=O) =O
Molecular Formula
C22H22F3N3O3S2
Molecular Weight
497.5536
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Thieno[3,2-c]pyridine-2-carboximidamide, 5-ethyl-4,5-dihydro-4-oxo-N- (tetrahydro-1,1-dioxido-2H-thiopyran-4-yl) -7-[3- (trifluoromethyl) phenyl]-
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