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I-BRD9

The first selective cellular chemical probe for BRD9 with pIC50 of 7.3; displays 700-fold selectivity over the BET family and 200-fold over the highly homologous BRD7; decreases cell proliferation, G1-arrest and apoptosis in rhabdoid tumor cells; shows synergistic inhibitory effects on cell proliferation combined with doxorubicin or carboplatin.

Product Specifications

CAS Number

1714146-59-4

Product Name Alternative

I-BRD9 | I-BRD-9 | I-BRD 9

Field of Research

Epigenetics & Chromatin

Purity

>98% (HPLC)

Solubility

DMSO: 15.5 mg/mL

Smiles

N=C (C (S1) =CC2=C1C (C3=CC=CC (C (F) (F) F) =C3) =CN (CC) C2=O) NC (CC4) CCS4 (=O) =O

Molecular Formula

C22H22F3N3O3S2

Molecular Weight

497.5536

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Thieno[3,2-c]pyridine-2-carboximidamide, 5-ethyl-4,5-dihydro-4-oxo-N- (tetrahydro-1,1-dioxido-2H-thiopyran-4-yl) -7-[3- (trifluoromethyl) phenyl]-

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