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BIX 01294 Trihydrochloride

BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases.

Product Specifications

CAS Number

1392399-03-9

Purity

>98% (HPLC)

Solubility

Ethanol: 8 mg/mL (13.33 mM) ; Water: 98 mg/mL (163.32 mM) ; DMSO: 98 mg/mL (163.32 mM)

Smiles

Cl.Cl.Cl.COC1=C (OC) C=C2C (NC3CCN (CC4=CC=CC=C4) CC3) =NC (=NC2=C1) N1CCCN (C) CC1

Molecular Formula

C28H38N6O2·3HCl

Molecular Weight

600.02

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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