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LDN212854

LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity for BMP versus the TGF-β type I receptors; possesses a bias towards ALK2 (IC50=1.3 nM) versus ALK1 and ALK3 compared to other inhibitors.

Product Specifications

CAS Number

1432597-26-6

Product Name Alternative

LDN212854 | LDN 212854 | LDN-212854

Purity

>98% (HPLC)

Solubility

DMSO: 81 mg/mL warmed (199.27 mM)

Smiles

C12=C (C3=C4N=CC (C5=CC=C (N6CCNCC6) C=C5) =CN4N=C3) C=CC=C1N=CC=C2

Molecular Formula

C25H22N6

Molecular Weight

406.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5- (6- (4- (piperazin-1-yl) phenyl) pyrazolo[1,5-a]pyrimidin-3-yl) quinoline

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