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Perifosine

A oral bioavailable alkylphospholipid that displays significant antiproliferative activity in vitro and in vivo in several human tumor model; acts as an Akt inhibitor and a PI3K inhibitor, induces p21 (WAF1) expression in squamous carcinoma cells through a p53-independent pathway; enhances apoptosis and inhibits the growth of xenografts in nude mice combined with a lysosomal inhibitor.Brain Cancer Phase 2 Clinical.

Product Specifications

CAS Number

157716-52-4

Product Name Alternative

KRX-0401 | NSC 639966 | D-21266 | KRX 0401 | KRX0401 | D21266 | D 21266

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=P (OC1CC[N+] (C) (C) CC1) ([O-]) OCCCCCCCCCCCCCCCCCC

Molecular Formula

C25H52NO4P

Molecular Weight

461.6584

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Piperidinium, 4-[[hydroxy (octadecyloxy) phosphinyl]oxy]-1,1-dimethyl-, inner salt

Available Sizes

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