Perifosine
A oral bioavailable alkylphospholipid that displays significant antiproliferative activity in vitro and in vivo in several human tumor model; acts as an Akt inhibitor and a PI3K inhibitor, induces p21 (WAF1) expression in squamous carcinoma cells through a p53-independent pathway; enhances apoptosis and inhibits the growth of xenografts in nude mice combined with a lysosomal inhibitor.Brain Cancer Phase 2 Clinical.
Product Specifications
CAS Number
157716-52-4
Product Name Alternative
KRX-0401 | NSC 639966 | D-21266 | KRX 0401 | KRX0401 | D21266 | D 21266
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=P (OC1CC[N+] (C) (C) CC1) ([O-]) OCCCCCCCCCCCCCCCCCC
Molecular Formula
C25H52NO4P
Molecular Weight
461.6584
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Piperidinium, 4-[[hydroxy (octadecyloxy) phosphinyl]oxy]-1,1-dimethyl-, inner salt
Available Sizes
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