LDN-214117
A potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM; displays 164-fold selectivity for BMP6 versus TGF-β1; a highly selective probes of BMP-mediated cellular physiology.
Product Specifications
CAS Number
1627503-67-6
Product Name Alternative
LDN214117
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
COC1=C (OC) C (OC) =CC (C2=C (C) N=CC (C3=CC=C (N4CCNCC4) C=C3) =C2) =C1
Molecular Formula
C25H29N3O3
Molecular Weight
419.5161
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Piperazine, 1-[4-[6-methyl-5- (3,4,5-trimethoxyphenyl) -3-pyridinyl]phenyl]-
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