LDN-214117

A potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM; displays 164-fold selectivity for BMP6 versus TGF-β1; a highly selective probes of BMP-mediated cellular physiology.

Product Specifications

CAS Number

1627503-67-6

Product Name Alternative

LDN214117

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

COC1=C (OC) C (OC) =CC (C2=C (C) N=CC (C3=CC=C (N4CCNCC4) C=C3) =C2) =C1

Molecular Formula

C25H29N3O3

Molecular Weight

419.5161

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Piperazine, 1-[4-[6-methyl-5- (3,4,5-trimethoxyphenyl) -3-pyridinyl]phenyl]-

Available Sizes

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