Semaxanib
Semaxanib (SU5416) is a potent and selective VEGFR (Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
Product Specifications
CAS Number
194413-58-6
Product Name Alternative
SU5416
Purity
>98% (HPLC)
Solubility
Ethanol: 2 mg/mL (8.39 mM) ; DMSO: 22 mg/mL (92.32 mM)
Smiles
CC1=CC (=C (N1) /C=C\2/C3=CC=CC=C3NC2=O) C
Molecular Formula
C15H14N2O
Molecular Weight
238.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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