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Z-JIB-04

JIB-04 Z-isomer, also known as NSC 693627, is an isomer of JIB-04. JIB-04 is a Jumonji histone demethylase inhibitor. JIB-04 selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. JIB-04 can prolong survival in a mouse model of breast cancer.

Product Specifications

CAS Number

199596-24-2

Product Name Alternative

NSC 693627

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

ClC1=CN=C (N/N=C (C2=CC=CC=C2) \C3=NC=CC=C3) C=C1

Molecular Formula

C17H13ClN4

Molecular Weight

308.76

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(Z) -5-chloro-2- (2- (phenyl (pyridin-2-yl) methylene) hydrazinyl) pyridine

Available Sizes

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