YO-01027
YO-01027 (Dibenzazepine) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM for APPL and Notch cleavage, respectively.
Product Specifications
CAS Number
209984-56-5
Product Name Alternative
Dibenzazepine
Purity
>98% (HPLC)
Solubility
DMSO:92 mg/mL (198.49 mM) ; Ethanol:<1 mg/mL (<1 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
C[C@H] (NC (CC1=CC (F) =CC (F) =C1) =O) C (N[C@@H]2C (N (C) C3=CC=CC=C3C4=CC=CC=C24) =O) =O
Molecular Formula
C26H23F2N3O3
Molecular Weight
463.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -2- (2- (3,5-difluorophenyl) acetamido) -N- ((S) -5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b, d]azepin-7-yl) propanamide
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