Purvalanol B
A potent, cell-permeable, selective inhibitor of CDK with IC50s of 6, 6, 9, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5-p35 respectively; no inhibition for cdk4/cyclin D1 (>10 uM) ; has no effect on Erk1, PKC, Raf, CK1, CK2.
Product Specifications
CAS Number
212844-54-7
Product Name Alternative
NG-95
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 40 mg/mL
Smiles
CC (C) N1C2=NC (N[C@H] (C (C) C) CO) =NC (NC3=CC (Cl) =C (C (O) =O) C=C3) =C2N=C1
Molecular Formula
C20H25ClN6O3
Molecular Weight
432.9039
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzoic acid, 2-chloro-4-[[2-[[ (1R) -1- (hydroxymethyl) -2-methylpropyl]amino]-9- (1-methylethyl) -9H-purin-6-yl]amino]-
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