Evans blue
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT) . Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively) .
Product Specifications
CAS Number
314-13-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 10 mM
Smiles
CC1=C (C=CC (=C1) C2=CC (=C (C=C2) N/N=C\3/C (=O) C4=C (C (=CC (=C4N) S (=O) (=O) [O-]) S (=O) (=O) [O-]) C=C3) C) N/N=C\5/C (=O) C6=C (C (=CC (=C6N) S (=O) (=O) [O-]) S (=O) (=O) [O-]) C=C5.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C34H24N6Na4O14S4
Molecular Weight
960.78
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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