TDZD-8
A potent, selective, non-ATP competitive GSK-3β inhibitor with IC50 of 2 uM; displays no activity against PKA, CK-2, PKC, and CDK1 (IC50>100 uM) ; reduces the colonic inflammation induced by TNBS in vivo, also prevents 6-OHDA-induced neuronal cell death.
Product Specifications
CAS Number
327036-89-5
Product Name Alternative
TDZD 8 | TDZD8 | GSK-3β Inhibitor I | NP 01139
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (N1CC2=CC=CC=C2) N (C) SC1=O
Molecular Formula
C10H10N2O2S
Molecular Weight
222.2636
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,2,4-Thiadiazolidine-3,5-dione, 2-methyl-4- (phenylmethyl) -
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