Isoconazole nitrate
Isoconazole nitrate (Travogen) is an azole antifungal reagent. (In Vitro) :Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.
Product Specifications
CAS Number
24168-96-5
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 4 mg/mL (8.34 mM) ; DMSO: 41 mg/mL (85.56 mM)
Smiles
O[N+] ([O-]) =O.ClC1=CC (Cl) =C (C=C1) C (CN1C=CN=C1) OCC1=C (Cl) C=CC=C1Cl
Molecular Formula
C18H14Cl4N2O·HNO3
Molecular Weight
479.14
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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