NH-125
A potent eukaryotic eEF-2 kinase (eEF2K) inhibitor with IC50 of 60 nM in vitro and blocks the phosphorylation of eEF-2 in intact cells; shows relative selectivity over other protein kinases: PKC (IC50=7.5 uM), PKA (IC (50=80 uM), and CaMKII (IC50>100 uM) ; shows efficacious anti-proliferation activityt against different cancer cells.
Product Specifications
CAS Number
278603-08-0
Product Name Alternative
NH 125 | NH125
Purity
>98% (HPLC)
Solubility
DMSO: 52.5 mg/mL (100 mM) ; Ethanol: 39.3 mg/mL (75 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
CC1=[N+] (CC2=CC=CC=C2) C=CN1CCCCCCCCCCCCCCCC.[I-]
Molecular Formula
C27H45IN2
Molecular Weight
524.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Imidazolium, 1-hexadecyl-2-methyl-3- (phenylmethyl) -, iodide (9CI)
Available Sizes
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