Doramapimod
A highly potent p38 MAPK inhibitor with Kd of 0.1 nM; displays no activity on ERK1, IKK2b, ZAP-70, EGFR, PKA, PKC, etc.; shows inhibition of TNFα inTHP.1 with IC50 of 18 nM; orally active.
Product Specifications
CAS Number
285983-48-4
Product Name Alternative
BIRB 796 | BIRB-796 | BIRB796
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC1=C2C=CC=CC2=C (OCCN3CCOCC3) C=C1) NC4=CC (C (C) (C) C) =NN4C5=CC=C (C) C=C5
Molecular Formula
C31H37N5O3
Molecular Weight
527.6572
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Urea, N-[3- (1,1-dimethylethyl) -1- (4-methylphenyl) -1H-pyrazol-5-yl]-N'-[4-[2- (4-morpholinyl) ethoxy]-1-naphthalenyl]-
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