Azlocillin sodium

Azlocillin is an acylampicillin with a broad spectrum against bacteria. (In Vitro) :Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin. (In Vivo) :Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.