Tenovin-1
Tenovin-1 (Tenovin1) is a small molecules that activate p53 and decreases tumor growth through inhibition of the protein-deacetylating activities of SirT1 and SirT2; causes significantly greater growth inhibition, cell death via apoptosis, as well as superior p53 promoter upregulation in wtp53 MyLa cells when combined with vorinostat; elicits caspase-mediated cell death in p53 wild-type cells, but caspase-independent cell death in p53 null cells.
Product Specifications
CAS Number
380315-80-0
Product Name Alternative
Tenovin 1
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC (NC1=CC=C (NC (C) =O) C=C1) =S) C2=CC=C (C (C) (C) C) C=C2
Molecular Formula
C20H23N3O2S
Molecular Weight
369.4805
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, N-[[[4- (acetylamino) phenyl]amino]thioxomethyl]-4- (1,1-dimethylethyl) -
Available Sizes
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