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Cortisone

Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress.Allergy Approved (In Vitro) :Cortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) . (In Vivo) :Cortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits.

Product Specifications

CAS Number

53-06-5

Product Name Alternative

17-Hydroxy-11-dehydrocorticosterone | Kendall's compound E

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

C[C@@]1 (C2) [C@] (C (CO) =O) (O) CC[C@@]1 ([H]) [C@]3 ([H]) CCC4=CC (CC[C@]4 (C) [C@@]3 ([H]) C2=O) =O

Molecular Formula

C21H28O5

Molecular Weight

360.444

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-

Available Sizes

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