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Nutlin-3

Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.

Product Specifications

CAS Number

548472-68-0

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

COC1=CC (OC (C) C) =C (C=C1) C1=NC (C (N1C (=O) N1CCNC (=O) C1) C1=CC=C (Cl) C=C1) C1=CC=C (Cl) C=C1

Molecular Formula

C30H30Cl2N4O4

Molecular Weight

581.49

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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